<i>Clerodendron inerme</i> Protects Cellular Integrity During 7,12- Dimethylbenz[A]-Anthracene Induced Hamster Buccal Pouch Carcinogenesis

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Clerodendron inerme protects cellular integrity during 7,12-dimethylbenz[A]-anthracene induced hamster buccal pouch carcinogenesis.

Aim of the present study was to investigate the protective effect of Clerodendron inerme on cellular integrity by measuring the status of glycoconjugates, lipids, osmotic fragility, and membrane bound enzyme activity in 7,12-dimethylbenz (a) anthracene (DMBA)-induced oral carcinogenesis. Oral squamous cell carcinoma was induced in the buccal pouch of Syrian golden hamsters by painting with 0.5%...

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Chemopreventive efficacy of curcumin and piperine during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.

INTRODUCTION Oral carcinoma accounts for 40-50 percent of all cancers in India. Tobacco chewing, smoking and alcohol consumption are the major risk factors associated with the high incidence of oral cancer in India. Our aim was to investigate the chemopreventive potential of curcumin and piperine during 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch carcinogenesis. METHODS...

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Lupeol Protects Abnormalities in Cell Surface Moities during 7, 12-dimethylbenz[a]anthracene Induced Hamster Buccal Pouch Carcinogenesis

Lupeol, a pentacyclic triterpene, possesses diverse pharmacological and biochemical activities including anticancer and antioxidant effects. Abnormalities in the status of glycoconjugates and lipids in the cell results in malignant transformation. The aim of the present study was to investigate the protective effect of lupeol on cell surface glycoconjugates and lipids abnormalities during 7,12-...

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Enicostemma Littorale Protects Cell Surface Abnormalities during Dmba-induced Hamster Buccal Pouch Carcinogenesis

Glycoconjugates [protein bound hexose, protein bound hexosamine, total sialic acid and fucose] play a pivotal role in neoplastic transformation if they are abnormally expressed. The protective effect of Enicostemma littorale leaves on cell surface abnormalities was analyzed by measuring the status of the above said glycoconjugates during 7,12dimethylbenz(a) anthracene (DMBA) induced hamster buc...

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Terminalia Arjuna (Roxb.) Modulates Circulatory Antioxidants on 7,12-dimethylbenz(a)anthracene- induced Hamster Buccal Pouch Carcinogenesis.

OBJECTIVES Oral cancer is the fifth most frequent cancer worldwide and India has recorded the highest incidence (40-50%) of oral malignancy. This study is designed to investigate the effect of aqueous extract of Terminalia arjuna bark (TaBet) on circulatory lipid peroxidation and antioxidant status during 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch carcinogenesis. METHO...

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ژورنال

عنوان ژورنال: African Journal of Traditional, Complementary and Alternative Medicines

سال: 2008

ISSN: 0189-6016

DOI: 10.4314/ajtcam.v5i2.31276